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Subgroup analysis.
| Subgroup | Sample size (n) | HR (95% CI) | I2 (%) | p-value |
|---|---|---|---|---|
| Region | ||||
| United States | 11 | 2.30 (1.94, 2.71) | 73.2 | <0.001 |
| Asians | 8 | 2.11 (1.71, 2.61) | 67.2 | <0.001 |
| Europeans | 4 | 1.8 (1.39, 2.34) | 86.4 | <0.001 |
| Pre-frailty | ||||
| Pre-frailty | 8 | 1.80 (1.46, 2.23) | 82.9 | <0.001 |
| Frailty | 8 | 3.13 (2.26, 4.34) | 75.9 | <0.001 |
Subgroup analyses of frailty’s link to cardiovascular mortality, categorized by region and pre-frailty.
