Figure 3.

B cell–deficient mice have altered kinetics of response to a CCl₄-induced liver injury. Mice of the genotype indicated were gavaged once with 1.75 ml/kg of CCl₄ or with mineral oil. Either 1, 3, or 5 days after treatment, mice were sacrificed, and immunohistochemical analyses of liver sections were performed. Magnification for apoptotic cell–specific TUNEL, macrophage-specific F4/80, and myofibroblast-specific α-SMA stainings, ×100.