TABLE 4.
Stability of sulfonate esters measured by H1-NMR spectroscopy
| Substance | Stability of compound (%)a | Released sulfonic acid |
|---|---|---|
| Busulfan | 0 | Unknown |
| Butanesultone | 100 | |
| (S)-1,2,4-Butanetriol-trimethane-sulfonate | 0 | Methane sulfonic acid |
| Ethyl methanesulfonate | 90 | Methane sulfonic acid |
| l-(−)-Methanesulfonyl-ethyllactate | 100 | |
| Methyl methanesulfonate | 72 | Methane sulfonic acid |
| Propanesultone | 22 | 3-Hydroxypropane sulfonic acid |
a
The values indicate the amount of original substance remaining after 24 h of incubation in D2O.