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. 2005 Oct 3;5:126. doi: 10.1186/1471-2407-5-126

Table 1.

Finnish Colorectal Cancers Sample

Cancer Type Average Age (years) Number (%) Most Likely Numbers of Mutations*

4 5 6 7 8 9
HNPCC 50.3 29 (2.9) 0.08 0.43 0.39 0.09
Sporadic MSI+ 71.5 98 (12.4) 0.03 0.2 0.34 0.33 0.1
Sporadic MSI- 67.5 895 (87.6) 0.01 0.99
Sporadic MSI-
Stage A 68.6 187 (21.2) 0.09 0.75 0.16
Stage B 69.0 330 (37.3) 0.44 0.56
Stage C 65.2 246 (27.8) 0.8 0.2
Stage D 65.4 121 (13.7) 0.06 0.66 0.28

* Probabilities of the number of mutations required for cancer. Most likely values are underlined.