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. 2002 Jun 27;99(15):9960–9965. doi: 10.1073/pnas.132254199

Figure 2.

Figure 2

Comparative analysis of the individual response to the nonmodified and the galactosylated T cell epitope in DR4 and huCII/DR4 mice. Recall in vitro response of lymph node cells from DR4 and huCII/DR4 mice immunized 10 days earlier with human CII. Cells were restimulated with either 10 or 50 μg/ml of the K264/270- or the Gal264-peptide. A ratio above 1 indicates a stronger response against the K264/270-peptide whereas a ratio below 1 indicates a stronger response to the Gal264-peptide. The response of individual DR4 mice was stronger to the K264-peptide whereas the responses of huCII/DR mice were stronger to the Gal264-peptide (Wilcoxon signed rank test).