Table 1. Genes differentially expressed in infected macrophages between congenic and parental lines, which are also common across the reciprocal congenic lines.
Gene symbol | Gene name | Chromosome, position | Fold change BALB/c v. C.lmr1/2 | Up or down | Fold change C57BL/6 v. B6.lmr1/2 | Up or down |
---|---|---|---|---|---|---|
1110008E19Rik | RIKEN cDNA | 17, A3.3 | 1.48 | D | 1.48 | U |
Tmsb10 | Thymosin, β10 | 2, 18.0 cM | 1.32 | U | 1.38 | D |
Cxcl2 | Chemokine (C-X-C motif) ligand 2 | 5, 51.0 cM | 3.25 | D | 1.57 | U |
2010100O12Rik | RIKEN cDNA | 2, H1 | 1.34 | U | 1.34 | D |
H2-D1 | Histocompatibility 2, D region locus 1 | 17, 19.09 cM | 3.99 | D | 3.83 | U |
Sdha | Succinate dehydrogenase complex, subunit A, flavoprotein | 13, C1 | 1.44 | U | 1.50 | D |
Pim1 | Proviral integration site 1 | 17, 16.4 cM | 1.77 | D | 1.50 | U |
Rpo1-1 | RNA polymerase 1-1 (40-kDa subunit) | 17, B3 | 1.81 | U | 1.85 | D |
— | IMAGE: 4192122, mRNA | — | 2.39 | D | 1.80 | U |
Acta2 | Actin, α2, | 19, C3 | 1.97 | U | 1.59 | D |
Rbbp7 | Retinoblastoma binding protein 7 | X, F4 | 1.47 | U | 1.51 | D |
H2-Ea | Histocompatibility 2, class II antigen E α | 17, 18.7 cM | 14.34 | D | 6.08 | U |
Ltb | Lymphotoxin B | 17, 19.06 cM | 1.67 | D | 1.70 | U |
— | RIKEN clone | — | 1.69 | U | 1.60 | D |
5730403E06Rik | RIKEN cDNA | X, A1.1 | 1.49 | U | 1.37 | D |
qk | Quaking | 17, 5.9 cM | 1.41 | U | 1.78 | D |
Col1a1 | Procollagen, type I, α1 | 11, 56.0 cM | 1.48 | U | 1.72 | D |
Fen1 | Flap structure specific endonuclease 1 | 19, A | 1.89 | U | 1.50 | D |
2310015N07Rik | RIKEN cDNA | 7, | 1.46 | U | 1.50 | D |
Ctgf | Connective tissue growth factor | 10, 17.0 cM | 2.17 | U | 1.56 | D |
1110008E19Rik | RIKEN cDNA | 17, A3.3 | 1.63 | D | 1.61 | U |
2610003J05Rik | RIKEN cDNA | 4, D3 | 1.38 | U | 1.36 | D |
Pbx3 | Pre-B cell leukemia transcription factor 3 | 2, 22.0 cM | 1.44 | U | 1.45 | D |
Zfp36 | Zinc finger protein 36 | 7, 10.2 cM | 2.08 | D | 1.43 | D |
H2-Aa | Histocompatibility 2, class II antigen A, α | 17, 18.65 cM | 1.36 | D | 1.50 | D |
Mapkapk2 | MAP kinase-activated protein kinase 2 | 1, E4 | 1.4 | D | 1.48 | D |
U, up in congenic; D, down in congenic. All comparisons with infected cells. MAP, mitogen-activated protein.