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. 2025 Aug 22;26(8):2899–2907. doi: 10.31557/APJCP.2025.26.8.2899

Tabel 1.

Top 10 GO Based on Gene Count

ID Term Count p-value
Biological Process
GO:0045944  Positive regulation of transcription by RNA polymerase II 11 1.90E-05
GO:0010628 Positive regulation of gene expression 9 1.10E-06
GO:0045893 Positive regulation of DNA-templated transcription 9 1.40E-05
GO:0007165 Signal transduction 9 6.40E-04
GO:0006357 Regulation of transcription by RNA polymerase II 9 3.40E-03
GO:0009410 Response to xenobiotic stimulus 8 1.40E-07
GO:0006915 Apoptotic process 8 3.70E-05
GO:0000122 Negative regulation of transcription by RNA polymerase II 8 7.40E-04
GO:0008285 Negative regulation of cell population proliferation 7 6.10E-05
GO:0043066 Negative regulation of apoptosis process 7 1.40E-04
Cellular Component
GO:0005737 Cytoplasm 24 5.70E-07
GO:0005634 Nucleus 23 1.10E-05
GO:0005829 Cytosol 21 5.30E-05
GO:0005654 Nucleoplasm 18 3.30E-05
GO:0016020 Membrane 15 1.60E-02
GO:0005886 Plasma membrane 15 3.70E-02
GO:0032991 Protein-containing complex 10 7.80E-07
GO:0005739 Mitochondrion 10 3.70E-04
GO:0000785 Chromatin 8 1.90E-03
GO:0005783 Endoplasmic reticulum 8 2.20E-03
Molecular Function
GO:0005515 Protein binding 33 1.70E-06
GO:0042802 Identical binding protein 19 1.90E-11
GO:0003677 DNA binding 9 4.70E-04
GO:0005524 ATP binding 9 3.00E-03
GO:0019899 Enzyme binding 8 2.10E-06
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 8 1.30E-05
GO:0003700 DNA-binding TF activity 8 2.30E-05
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding 8 4.30E-03
GO:0000981 DNA-binding TF activity, RNA polymerase II-specific 8 6.00E-03
GO:0061629 RNA polymerase II-specific DNA-binding TF binding 7 5.10E-07

*TF, transcription factor