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PDI overexpression prevents the development of insulin resistance in HFD-challenged mice. (A) Body weights (B) IPGTT, (C) ITT and (D) FBG were measured in HFD-fed mice after PDI overexpression. (E) Glycogen deposition and (F) the mRNA levels of G6PC and PEPCK and (G) protein expression of PDI, p-AKT and p-GSK3β were determined in the livers of mice overexpressing PDI and in the controls
