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. Author manuscript; available in PMC: 2005 Nov 1.
Published in final edited form as: Endocrinology. 2005 Aug 11;146(11):4737–4744. doi: 10.1210/en.2005-0279

Fig. 5. Effect of Fas activation on the metabolic activity of anterior pituitary cells.

Fig. 5

A, Anterior pituitary cells from OVX rats cultured with 17β-estradiol (10−9 M) were incubated with an agonistic anti-Fas antibody, (Mab-Fas, 0.1–10 μg/ml) for 6 h. Cell viability was assessed by the MTT assay. Each column represents the mean ± SE of 10 wells. * p < 0.05; ** p < 0.01 vs control. (One-way ANOVA followed by Dunnet multiple comparison test). B, Anterior pituitary cells from OVX rats cultured with vehicle (ethanol 1 μl/l, VEH) or 17β-estradiol (10−9 M, E2) were incubated in the presence of recombinant FasL (10 ng/ml, FasL) for 16 h and cell viability was assessed by the MTS assay. Each column represents the mean ± SE of 10 wells. * p < 0.05 vs respective control without FasL; ^ p < 0.05 vs respective control without 17β-estradiol. (Two-way ANOVA followed by Tukey test).