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. 2005 Oct 28;1(2):e21. doi: 10.1371/journal.ppat.0010021

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Copyright: © 2005 Coloma and Harris.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The collection of samples, monitored here by Eva Harris (right), is part of the UC Berkeley/SSI pediatric dengue cohort study in Managua, Nicaragua. Objectives of this study include investigating the natural history and risk factors for dengue virus transmission and disease, obtaining biological samples in parallel with clinical and epidemiological information, and establishing a site for a future phase III trial of a safe tetravalent dengue vaccine.

(Photo: Alejandro Belli)