Table 2.
Differences between patients having a Fluid Retention Index (FRI) of >4.0 on admission to hospital as evidence of strong renal water conservation before the surgery.
| FRI ≤ 4.0 (N = 857) |
FRI > 4.0 (N = 64) |
Odds ratio or difference (95% CI) | P-value | |
|---|---|---|---|---|
| FRI (mean score) | 2.1 ± 0.9 | 4.7 ± 0.5 | 2.58 (2.35–2.81) | <0.001 |
| Age (yr) | 61.3 ± 11.9 | 52.6 ± 12.6 | 8.92 (5.85–12.0) | <0.001 |
| Females (%) | 48 | 34 | 0.58 (0.34–0.98) | 0.049 |
| ASA I, II, III* | 78/20/2 | 80/16/4 | – | 0.12 |
| Infused ringer | ||||
| Volume (mL) | 1,974 ± 708 | 2,320 ± 848 | 345 (161–529) | <0.001 |
| >3 L (%) | 5.7 | 14.3 | 2.75 (1.28–5.89) | 0.007 |
| Infused Voluven (mL) | ||||
| Incidence (%) | 93% | 94% | – | 0.85 |
| Volume (mL) | 551 ± 177 | 717 ± 250 | 151 (75–228) | 0.001 |
| Urine (mL) | 380 (200–600) | 200 (118–500) | 100 (50–170) | 0.003 |
| Urine flow (mL/min) | 1.6 (0.9–2.5) | 0.9 (0.6–1.7) | 0.70 (0.23–1.21) | <0.001 |
| Baseline (mmHg) | 92 ± 12 | 89 ± 10 | 3.4 (0.4–6.4) | 0.03 |
| Surgery/baseline (ratio) | 0.95 ± 0.14 | 1.01 ± 0.17 | 0.062 (0.39–1.05) | 0.002 |
| Blood loss | ||||
| Volume (mL) | 80 (50–120) | 100 (30–170) | 42 (10–73) | 0.01 |
| >500 mL (%) | 1 | 5 | 4.86 (1.28–18.43) | 0.04 |
| Extubation time (min) | 27 (18–40) | 30 (21–50) | 5 (1–10) | 0.001 |
| P-glucose (mmol/L) | ||||
| Baseline | 5.0 ± 0.6 | 5.1 ± 0.5 | – | 0.47 |
| Postoperative | 6.6 ± 1.8 | 5.8 ± 1.6 | 0.88 (0.33–1.43) | 0.006 |
| P-creatinine (μmol/L) | ||||
| Baseline | 65.6 ± 13.7 | 63.5 ± 14.2 | – | 0.21 |
| Change (%) | +0.7 ± 16.0 | −4.4 ± 16.0 | 3.42 (0.61–6.24) | 0.017 |
| Paralytic ileus (days) | 1.5 ± 1.3 | 2.4 ± 2.3 | 0.81 (0.46–1.16) | 0.001 |
| Food intolerance (days) | 2.4 ± 2.3 | 3.9 ± 3.2 | 1.52 (0.70–2.35) | 0.011 |
| Infection (%) | ||||
| Respiratory | 21 | 19 | 0.87 (0.46–1.67) | 0.72 |
| Wound | 10 | 17 | 1.99 (1.00–3.96) | 0.046 |
| Fever | 17 | 28 | 1.89 (1.07–3.35) | 0.03 |
The statistical test was one-way ANOVA or the Mann–Whitney’s U test depending on data distribution. Categorical data were evaluated by the chi-square test. Bonferroni correction of the p-values to account for multiple testing was applied.
FRI, Fluid Retention Index; MAP, mean arterial pressure; ASA, American Society of Anesthesiologists (scale for physical health).
The inclusion of ASA class III is a protocol violation.