TABLE 1.
Demographic and clinico-pathological data.
| Variable | Total n = 32 |
|---|---|
| Age at diagnosis | |
| median (range) IQR |
7.0 (2–18) years 3–13 years |
| Sex | |
| Female/male | 17/15 (53%/47%) |
| ALL subtype | |
| common/pre-B | 26 (81%)/6 (19%) |
| Risk group (ALLIC-BFM-2009) | |
| standard/intermediate/high | 3 (9.4%)/22 (68.7%)/7 (21.9%) |
| Blast count in bone marrow | |
| median (range), IQR | 90 (25%–100%), 83%–98% |
| Response to prednisone, day 8 | |
| good (<1.0 × 109/L)/poor (≥1.0 × 109/L) blasts in blood | 28 (88%)/4 (13%) |
| Minimal residual disease, day 15 | |
| <0.1%/0.1%–10%/>10%/unknown | 11 (37%)/14 (47%)/5 (17%)/2 |
| Acute severe toxicity related to treatment | |
| Yes/No/unknown | 9 (29%)/22 (68%)/1 (3%) |
| Relapse | |
| Yes | 5 (16%) |
| Death | |
| Yes | 5 (16%) |
| Follow-up time (months) | |
| median (range) IQR |
32 (2–52) months 25–35 months |
IQR, interquartile range.