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. 2025 Nov 17;16:1701680. doi: 10.3389/fphar.2025.1701680

TABLE 1.

Demographic and clinico-pathological data.

Variable Total n = 32
Age at diagnosis
median (range)
IQR
7.0 (2–18) years
3–13 years
Sex
Female/male 17/15 (53%/47%)
ALL subtype
common/pre-B 26 (81%)/6 (19%)
Risk group (ALLIC-BFM-2009)
standard/intermediate/high 3 (9.4%)/22 (68.7%)/7 (21.9%)
Blast count in bone marrow
median (range), IQR 90 (25%–100%), 83%–98%
Response to prednisone, day 8
good (<1.0 × 109/L)/poor (≥1.0 × 109/L) blasts in blood 28 (88%)/4 (13%)
Minimal residual disease, day 15
<0.1%/0.1%–10%/>10%/unknown 11 (37%)/14 (47%)/5 (17%)/2
Acute severe toxicity related to treatment
Yes/No/unknown 9 (29%)/22 (68%)/1 (3%)
Relapse
Yes 5 (16%)
Death
Yes 5 (16%)
Follow-up time (months)
median (range)
IQR
32 (2–52) months
25–35 months

IQR, interquartile range.