Fig. 2. Activity of MCCB5, CB6 and MJM364. Compounds were tested for activity against the T7FFLuc control, the BUNV or the EBOV MG. The compounds were added to BSR-T7 cells at the indicated concentrations immediately before transfection. Cells were harvested at 24 hpt and analysed for FF-luc (EBOV MG and T7FFLuc control) or R-luc (BUNV MG), or cell viability by MTT assay. Values are represented as percentages of a transfection-only control. Graphs show dose–response curves for % RLU (left) and cytotoxicity (right). (a) MCCB5, (b) CB6 and (c) MJM364. EBOV, red circles. T7FFLuc control, blue squares. BUNV control, black diamonds. Averages plotted from three independent experiments performed in triplicate. Error bars show sd.