Table 2.
Comparison of primary outcomes (treatment metrics) between patients treated with rt-PA and patients treated with TNK
| Overall (n = 139) | All patients (n = 139) | rt-PA group (n = 65) | TNK group (n = 74) | p-value |
|---|---|---|---|---|
| DTN time [min] (median (IQR)) | 26 (33–18) | 28 (33–22) | 23 (32–17) | 0.047 |
| Golden hour IVT (n (%)) | 13 (9.4) | 3 (4.6) | 10 (13.5) | 0.088 |
| DTN time < 30 min (n (%)) | 81 (58.3) | 34 (52.3) | 47 (63.5) | 0.147 |
| Subgroup of patients with EVT ( n = 41) | ( n = 41) | ( n = 24) | ( n = 17) | |
| Needle-to-groin time [min] (median (IQR)) | 48 (53–41) | 49 (53–44) | 44.5 (50–36) | 0.096 |
| DTG time [min] (median (IQR)) | 65 (75–59) | 71 (78–65) | 61 (63–57) | 0.002 |
rt-PA Alteplase, TNK Tenecteplase, DTN Door-to-needle, min Minutes, IVT Intravenous thrombolysis, EVT Endovascular thrombectomy, DTG Door-to-groin, IQR Interquartile range, EVT Endovascular thrombectomy
Numbers written in bold indicate statistically significant group comparisons