Table 2. Bone histology and histomorphometric parameters according to fracture status.
| Patients with fractures during follow-up n = 5 (9.3%) |
Patients without fractures during follow-up n = 49 (90.7%) |
p-Value | |
|---|---|---|---|
| Bone histomorphometric results, n (%) | 0.847 | ||
| Normal bone | 3 (60) | 19 (38.8) | |
| Adynamic bone disease | 1 (20) | 19 (38.8) | |
| Hyperparathyroid bone disease | 1 (20) | 10 (20.4) | |
| Mixed uremic osteodystrophy | 0 (0) | 1 (2) | |
| BFR/BS, mm3/mm2/year, median (IQR) | 15.5 (5.2–20.4) | 15.5 (8.9–38.0) | 0.303 |
| Turnover, n (%) | 0.833 | ||
| Normal | 3 (60) | 19 (38.8) | |
| Low | 1 (20) | 19 (38.8) | |
| High | 1 (20) | 11 (22.4) | |
| Mineralization lag time, days, median (IQR) | 5.9 (5.2–5.9) | 21 (13.6–35.6) | 0.121 |
| Mineralization, n (%) | 1.000 | ||
| Normal | 5 (100) | 48 (98) | |
| Abnormal | 0 | 1 (2) | |
| BV/TV, %, median (IQR) | 16.1 (11.9–17.2)* | 19.0 (16.2–23.5)* | 0.057 |
| Bone volume, n (%) | 0.579 | ||
| Normal | 3 (60) | 24 (49) | |
| Low | 2 (40) | 12 (24.5) | |
| High | 0 | 13 (26.5) |
Abbreviations – IQR: interquartile range; BFR/BS: bone formation rate/bone surface; BV/TV: bone volume/tissue volume.