Table 4.
Cox model for AlcHepNet OBS AH cases (90-day mortality)
| Maximum Likelihood Estimates | ||||||||
|---|---|---|---|---|---|---|---|---|
| Parameter | DF | Parameter Estimate | Standard Error | Chi-Square | Pr > ChiSq | Hazard Ratio | 95% Hazard Ratio Confidence Limits | |
| Age at OBS enrollment | 1 | 0.02064 | 0.01115 | 3.4304 | 0.0640 | 1.021 | 0.999 | 1.043 |
| Gender assigned at birth: Male | 1 | −0.30578 | 0.28541 | 1.1478 | 0.2840 | 0.737 | 0.421 | 1.289 |
| Race: White | 1 | −0.43163 | 0.34616 | 1.5548 | 0.2124 | 0.649 | 0.330 | 1.280 |
| BMI | 1 | 0.00567 | 0.01565 | 0.1310 | 0.7174 | 1.006 | 0.975 | 1.037 |
| Education status: College education | 1 | −0.64032 | 0.23804 | 7.2358 | 0.0071 | 0.527 | 0.331 | 0.840 |
| Marital status: Married | 1 | 0.21169 | 0.23844 | 0.7882 | 0.3746 | 1.236 | 0.774 | 1.972 |
| Age of first drink | 1 | 0.01205 | 0.01772 | 0.4628 | 0.4963 | 1.012 | 0.978 | 1.048 |
| Alcohol use at baseline: Yes | 1 | 0.14053 | 0.30834 | 0.2077 | 0.6486 | 1.151 | 0.629 | 2.106 |
| Steroid use: At least once | 1 | −0.15757 | 0.27697 | 0.3237 | 0.5694 | 0.854 | 0.496 | 1.470 |
| MELD score | 1 | 0.09580 | 0.01641 | 34.0910 | <.0001 | 1.101 | 1.066 | 1.137 |
| Albumin | 1 | 0.06117 | 0.21135 | 0.0838 | 0.7722 | 1.063 | 0.703 | 1.609 |
| ALT | 1 | 0.00686 | 0.00459 | 2.2342 | 0.1350 | 1.007 | 0.998 | 1.016 |
| AST | 1 | 0.00155 | 0.00199 | 0.6017 | 0.4379 | 1.002 | 0.998 | 1.005 |
| Alkaline Phosphatase | 1 | −0.00445 | 0.00180 | 6.1452 | 0.0132 | 0.996 | 0.992 | 0.999 |
| Total Protein | 1 | −0.07420 | 0.14270 | 0.2704 | 0.6031 | 0.928 | 0.702 | 1.228 |
| Hemoglobin | 1 | 0.05679 | 0.07780 | 0.5329 | 0.4654 | 1.058 | 0.909 | 1.233 |
| Total WBC (x 10^9 /L) | 1 | 0.03518 | 0.01237 | 8.0809 | 0.0045 | 1.036 | 1.011 | 1.061 |
| Platelet Count (10^9 /L) | 1 | −0.00149 | 0.00154 | 0.9351 | 0.3335 | 0.999 | 0.996 | 1.002 |
| MCV | 1 | −0.02193 | 0.01332 | 2.7107 | 0.0997 | 0.978 | 0.953 | 1.004 |
| MAP | 1 | −0.03040 | 0.01236 | 6.0485 | 0.0139 | 0.970 | 0.947 | 0.994 |
Abbreviations: AH: Alcoholic hepatitis; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; BMI: Body Mass Index; MAP: Mean Arterial Pressure; MCV: Mean Corpuscular Volume; MELD: Model for End-Stage Liver Disease; OBS: Observational; Pr > ChiSq: Probability greater than Chi-Square; WBC: White Blood Cell Count