TABLE 2.

Antipyretic activity of folenolide using brewer’s yeast.

Group	Temperature before yeast administration Mean ± SD °F	Temperature control pre-drug administration Mean ± SD °F	Rectal temperature after drug administration in mean ± SD °F (p-value)
			1 h	2 h	3 h	4 h	5 h
Control	98.07 ± 0.06	101.42 ± 0.38	101.65 ± 0.41	101.68 ± 0.18	101.80 ± 0.16	101.65 ± 0.22	101.36 ± 0.94
Standard	98.80 ± 0.50	101.59 ± 0.21	99.30 ± 0.52 (0.0035)**	99.13 ± 0.51 (0.0012)**	98.83 ± 0.68 (0.0018)**	98.90 ± 0.45 (0.0006)***	98.53 ± 0.21 (0.0001)***
3 mg/kg	98.80 ± 0.36	101.53 ± 0.37	98.57 ± 0.26 (0.0004)***	98.43 ± 0.23 (<0.0001)***	98.50 ± 0.30 (<0.0001)***	98.43 ± 0.17 (<0.0001)***	98.47 ± 0.30 (0.0002)***
6 mg kg	98.50 ± 0.15	101.09 ± 0.24	99.30 ± 0.62 (0.0054)**	99.20 ± 0.72 (0.0044)**	99.20 ± 0.20 (<0.0001)***	98.60 ± 0.09 (<0.0001)***	98.63 ± 0.11 (<0.0001)***