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. 2025 Nov 19;12:1721952. doi: 10.3389/fmed.2025.1721952

Table 2.

Clinical manifestations and laboratory findings after intubation.

Successful extubation (n = 22) Failed extubation (n = 81) t/Z p
Vital signs
 Body temperature (°C) 36.78 (0.86) 36.89 (1.16) −0.404 0.687
 SBP (mmHg) 131.95 (25.85) 106.00 (95.00, 131.00) −2.930 0.003
 DBP (mmHg) 75.50 (23.11) 60.00 (46.00, 68.00) −2.918 0.004
Pulse pressure (mmHg) 62.00 (31.00, 79.00) 48 (40.00, 65.00) −1.107 0.268
 MAP (mmHg) 94.36 (20.42) 75.00 (65.00, 86.00) −3.200 0.001
 HR (bpm) 98.73 (20.46) 105.21 (25.29) −1.107 0.271
 SPO2 (%) 100.00 (99.00, 100.00) 100.00 (98.00, 100.00) −0.743 0.457
Laboratory results
 White blood cell count (*109/L) 11.42 (5.49) 12.40 (8.50, 17.42) −1.219 0.223
 Neutrophilic percentage (%) 88.30 (81.45, 93.00) 89.20 (81.60, 92.90) −0.402 0.687
 Lymphocyte count (*109/L) 0.75 (0.31, 1.08) 0.70 (0.40, 1.47) −0.109 0.913
 Hemoglobin concentration (g/L) 97.18 (31.29) 96.33 (25.83) 0.130 0.896
 Platelet count (*109/L) 188.00 (148.00, 231.00) 158.22 (77.96) −1.316 0.188
 CRP (mg/L) 47.88 (19.84, 93.44) 62.49 (22.63 28.60) −0.978 0.328
 PCT (ng/L) 2.36 (0.26, 3.97) 1.0.52 (0.54, 4.56) −0.089 0.929
 Albumin (g/L) 31.63 (3.17) 30.48 (4.20) 1.194 0.235
 Total protein (g/L) 58.91 (55.78, 63.40) 57.16 (7.50) −1.006 0.314
 ALT (U/L) 30.00 (19.00, 42.00) 19.00 (12.00, 56.00) −0.539 0.590
 AST (U/L) 49.00 (23.00, 59.00) 39.00 (22.00, 123.00) −0.394 0.693
 Scr ( μ mol/L) 100.5 (76.00, 183.00) 130.00 (95.00, 209.00) −1.432 0.152
 BUN (mmol/L) 12.52 (6.73, 19.01) 16.69 (11.76, 27.39) −2.567 0.010
 GFR (mL/min/1.73m2) 56.75 (30.04) 37.80 (20.30, 62.70) −1.963 0.050
 Serum sodium (mmol/L) 139.67 (5.29) 144.43 (8.57) −2.257 0.024
 Serum potassium (mmol/L) 4.26 (3.60, 4.65) 4.31 (3.94, 4.69) −0.608 0.543
 BNP (pg/mL) 519.00 (250.00, 776.00) 360.00 (198.00, 705.00) −0.933 0.351

HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; WBC, white blood cell count; CRP, C-reactive protein; PCT, procalcitonin; ALT, alanine transaminase; AST, aspartate transaminase; Scr, serum creatinine; BUN, blood urea nitrogen; GFR, glomerular filtration rate; BNP, B-type natriuretic peptide.The bold values represent statistical differences in this measure.