Table 2.

Evaluation of the relation between blood parameters and imaging findings with the possibility of malignancy in thyroid follicular neoplasm in the studied subjects

Variant	Malignant mass	Benign mass	p
WBC	7.77 (±1.6)	7.64 (±1.7)	0.723*
Neutrophil	4.61 (±1.5)	4.55 (±1.4)	0.864*
Lymphocyte	2.50 (±0.6)	2.36 (±0.4)	0.206*
Monocyte	0.43 (±0.3)	0.41 (±0.1)	0.728*
Platelet	271.74 (±51.8)	243.85 (±49.0)	0.015*
Hemoglobin	13.67 (±1.5)	13.53 (±1.3)	0.645*
CRP	3.0 (0.8–4.4)	2.1 (0.3–3.3)	0.376**
TSH	1.8 (1.1–4.2)	1.8 (1.1–2.7)	0.464**
Free T4	7.2 (2.3–9.8)	7.3 (2.1–8.6)	0.991**
Free T3	1.8 (1.4–2.9)	3.3 (1.5–100.2)	0.195**
NLR	1.6 (1.3–2.1)	2.0 (1.3–2.5)	0.291**
PLR	105.1 (86.1–135.2)	101.9 (84.8–123.1)	0.491**
Echogenicity, n (%)			0.681***
Hypoechoic	18 (20.5)	18 (20.5)
Hyperechoic	5 (5.7)	6 (6.8)
Isoechoic	11 (12.5)	18 (20.5)
Mixed echoic	4 (4.5)	8 (9.1)
Sonographic view, n (%)			0.462****
Solid	26 (29.5)	39 (44.3)
Cystic	4 (4.5)	2 (2.3)
Solid-cystic	8 (9.1)	9 (10.1)
Nodule, n (%)			0.104***
Solitary	18 (20.7)	33 (37.9)
Multinodular	19 (21.8)	17 (19.5)
Microcalcification, n (%)			0.014***
Positive	13 (14.9)	6 (6.9)
Negative	25 (28.7)	43 (49.4)
Nodule size (cm), n (%)			0.797***
<4 cm	25 (29.1)	36 (41.0)
≥4 cm	11 (12.8)	14 (16.3)

*: P-value by Independent Samples T-test; **: P-value by Mann-Whitney test; ***: P-value by Chi-square test; ****: P-value by Fisher’s Exact test; WBC: White blood cell; CRP: C-reactive protein; TSH: Thyroid-stimulating hormone; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio.