Table 3.
Secondary outcomes: time to mobilization; need of analgesic rescue dose; postoperative adverse events, numeric rate scale (NRS) and pain assessment in advanced dementia (PANAID) scores; length of stay
| Group SSA (N = 30) | Group PNBs (N = 30) | N = 60 | |
|---|---|---|---|
| Mean (SD) | Mean (SD) | p-value* | |
| Time to mobilization (hours) | 5.57 (1.06) | 8.2 (0.71) | < 0.001 |
| N (%) | N (%) | p-value* | |
| Need of analgesic rescue dose | 2 (6.67%) | 3 (1%) | ° |
| Postoperative adverse events | |||
| Rate of nausea/vomiting | 8 (26.67%) | 3 (10%) | 0.095 |
| Postoperative delirium | 13 (43.33%) | 4 (13.33%) | 0.021 |
| DVT | 0 (0%) | 0 (0%) | ° |
| MI | 0 (0%) | 0 (0%) | ° |
| Neurological lesion | 0 (0%) | 0 (0%) | ° |
| Median (IQR) | Median (IQR) | p-value* | |
| NRS (points) | |||
| At the end of the surgery | 1 (1–1)¥ | 1 (1–1) ¥ | ° |
| At 6 h after surgery | 2 (2–3) | 1.5 (1–3) | 0.076 |
| At 12 h after surgery | 3 (2–3.75) | 3 (2–3)θ | 0.454 |
| At 24 h after surgery | 2 (2–3) | 2 (2–3) | 0.023 |
| p-value | < 0.001 | < 0.001 | |
| PAINAD (points) | |||
| At the end of the surgery | 1 (1–1) ¥ | 1 (1–1) ¥ | 1 |
| At 6 h after surgery | 3 (2–5) £ | 2 (2–2)$ | < 0.001 |
| At 12 h after surgery | 3 (2–5) | 2 (2–3) | 0.177 |
| At 24 h after surgery | 3 (2–3.75) | 2 (2–3) | 0.848 |
| p-value | < 0.001 | < 0.001 | |
| Lenght of stay (days) | 2.25 (2–2.75) | 2 (1.81–2.5) | 0.045 |
SSA (selective spinal anesthesia), PNBs (peripheral nerve blocks), DVT (deep vein thrombosis), MI (myocardial infraction), IQR (interquartile range), SD (standard deviations)
*Continuous non-parametric data were compared with Mann–Whitney test, dichotomous data were compared with χ2test
°The data were practically constant
¥p < 0.05 compared to subsequent controls
Θp < 0.05 compared to 6 and 24 h after surgery
£p < 0.05 compared to 24 h after surgery
$ p < 0.05 compared to subsequent controls