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. 2025 Nov 28;2025:5558870. doi: 10.1155/ijpe/5558870

Table 3.

Subgroup analysis of the demographics and characteristics of infants undergoing procedural PDA closure between January 2017 and April 2023.

T o t a l = 46 TCDC ( n = 15) Ligation ( n = 31) p value
Gestation at birth (weeks), median (range) 26 (23–29) 27 (23–29) 25 (24–29) 0.092
Birth weight, median (range) 851.5 (450–1557) 890 (479–1220) 843 (450–1557) 0.527
Male sex, N (%) 27 (66%) 12 (80%) 15 (48%) 0.085
Small for gestational age, N (%) 17 (37%) 9 (60%) 8 (26%) 0.054
Antenatal steroids, any, N (%) 46 (100%) 15 (100%) 31 (100%) 0.999
Chronological age at time of closure (days), median (range) 34 (8–96) 44 (14–96) 31 (8–96) 0.052
Gestational age at time of closure (weeks), median (range) 30 (27–42) 33 (29–42) 30 (27–41) 0.021
Weight at time of closure (grams), median (range) 1278 (574–3690) 1430 (800–3690) 1158 (574–3672) 0.018
Medical treatment (yes), N (%) 44 (96%) 14 (93%) 30 (97%) 0.999
Invasive mechanical ventilation (yes), N (%) 23 (50%) 5 (33%) 18 (58%) 0.208
Inotropes (yes), N (%) 1 (2%) 0 1 (3%) 0.999
Feeding status prior to referral (any enteral feeds), N (%) 11 (24%) 13 (87%) 9 (29%) < 0.001