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. 2025 Nov 28;2025:5558870. doi: 10.1155/ijpe/5558870

Table 4.

Admission echocardiogram data at surgical center of infants prior to nonpharmacological PDA closure.

All ( n = 136) TCDC ( n = 15) Ligation ( n = 121) p value
Absolute PDA diameter (mm), median (range) 2.5 (1.5–4.1) 2.5 (2–3.5) 2.6 (1.5–4.1) 0.609
PDA diameter indexed to body weight (mm/kg), median (range) 2.42 (0.70–6.23) 1.61 (0.83–3.38) 2.60 (0.70–6.23) < 0.001
Direction of shunt: Left to right, N (%) 130 (100%)
n = 130
15 (100%)
n = 15
115 (100%)
n = 115
0.999
PDA Doppler profile–pulsatile yes, N (%) 113 (92%)
n = 123
15 (100%)
n = 15
98 (91%)
n = 108
0.609
Doppler peak systolic velocity (m/s), N (%) 2.3 (1.0–3.9)
n = 118
2.6 (1.2–3.6)
n = 15
2.25 (1.0–3.9)
n = 103
0.052
Presence of atrial shunt (yes), N (%) 121 (92%)
n = 131
13 (87%)
n = 15
108 (93%)
n = 116
0.321
Size of atrial shunt, N (%)
 Small 93 (78%) 11 (79%) 82 (77%) 0.730
 Moderate 27 (23%)
n = 120
2 (14%)
n = 13
25 (23%)
n = 107
Direction of atrial shunt left to right, N (%) 118 (98%)
n = 120
13 (100%)
n = 13
105 (98%)
n = 107
0.999