Table 3.

Odds Ratios (ORs) and 95% Confidence Interval (95% CI) of severe coronary artery disease (CAD) according to quartiles of TyG-BMI index, dietary insulin load, and dietary insulin index

Variable	Q1	Q2	Q3	Q4	P for trend
Triglyceride-glucose (TyG)-body mass index (BMI) Index
Median	202.81	234.70	263.61	313.84
Cases/non-cases	80/153	89/143	91/142	105/127
Model 1	1.00	1.21 (0.83–1.77)	1.24 (0.85–1.82)	1.64 (1.12–2.39)	0.011
Model 2	1.00	1.16 (0.78–1.73)	1.33 (0.89–1.99)	1.98 (1.31–2.99)	0.001
Energy-adjusted Dietary Insulin Load
Median	514.72	557.99	589.56	625.64
Cases/non-cases	63/170	71/161	99/134	132/100
Model 1	1.00	1.20 (0.80–1.80)	2.03 (1.37–3.00)	3.63 (2.45–5.37)	<0.001
Model 2*	1.00	1.32 (0.86–2.02)	2.19 (1.45–3.33)	4.28 (2.81–6.51)	<0.001
Model 3**	1.00	1.05 (0.65–1.68)	1.47 (0.89–2.42)	2.41 (1.41–4.12)	<0.001
Energy-adjusted Dietary Insulin Index
Median	37.81	41.13	43.53	46.17
Cases/non-cases	61/172	74/158	104/129	126/106
Model 1	1.00	1.32 (0.88–1.98)	2.31 (1.56–3.41)	3.40 (2.30–5.04)	<0.001
Model 2*	1.00	1.51 (0.98–2.33)	2.59 (1.70–3.94)	4.03 (2.64–6.14)	<0.001
Model 3**	1.00	1.22 (0.76–1.95)	1.65 (1.01–2.72)	2.22 (1.29–3.82)	0.002

Model 1: Adjusted for age and gender

Model 2 (TyG-BMI): Additionally adjusted for education, smoking, opium use, LVEF category, physical activity, hypertension, prediabetes/diabetes, dyslipidemia, antidiabetic medication, antihyperlipidemic medication, and energy-adjusted dietary insulin load

Model 2* (Dietary Indices): Additionally adjusted for education, smoking, opium use, LVEF category, physical activity, hypertension, prediabetes/diabetes, dyslipidemia, antidiabetic medication, antihyperlipidemic medication, and TyG-BMI index

Model 3**: Further adjusted for total fiber, fruits, vegetables, meat, dairy, total fat (all in grams/day), and total energy intake (Kcal/day)