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. 2025 Nov 19;61:100681. doi: 10.1016/j.ahjo.2025.100681

Table 1.

Baseline characteristics based on the CVDs subjects.

Characteristics CVDs
χ2/t P
Overall (N = 5402) Non-CVDS (N = 3943) CVDs (N = 1459) %
Age 2.673 0.102
 40–59 2857 2112 745 26.08
 60–79 2545 1831 714 28.06
Gender 0.078 0.781
 Male 2649 1929 720 27.18
 Female 2753 2014 739 26.84
Ethnicity 8.449 0.015*
 Mexican American 808 615 193 23.89
 Other Hispanic 582 441 141 24.23
 Others 4012 2887 1125 28.04
Marital status 16.920 <0.001**
 Married and living with partner 3495 2615 880 25.18
 Never married 444 310 134 30.18
 Others 1462 1017 445 30.44
Education status 2.885 0.236
 Less than high school 1347 963 384 28.51
 High school or GED 1189 862 327 27.50
 College and above 2866 2118 748 26.10
Family poverty income ratio 34.892 <0.001**
 <1.0 263 168 95 36.12
 1.0–2.0 2646 1867 779 29.44
 ≧3.0 2493 1908 585 23.47
BMI 17.744 <0.001**
 Normal 1291 980 311 24.09
 Overweight 1890 1408 482 25.50
 Obesity 2221 1555 666 29.99
Vigorous physical activity 13.365 <0.001**
 Yes 950 648 302 31.79
 No 4452 3295 1157 25.99
Moderate physical activity 27.006 <0.001**
 Yes 1946 1339 607 31.19
 No 3456 2604 852 24.65
Sleep disturbance 237.412 <0.001**
 Yes 1646 970 676 41.07
 No 3756 2973 783 20.85
Alcohol status 1.560 0.212
 Yes 3864 2802 1062 27.48
 No 1538 1141 397 25.81
Smoke status 37.470 <0.001**
 Yes 2707 1876 831 30.70
 No 2695 2067 628 23.30
TyG 5402 8.72 ± 0.67 8.79 ± 0.68 11.847 <0.001**
Serum alpha-Klotho levels 5402 858.37 ± 306.34 859.49 ± 366.05 0.013 0.910
Serum alpha-Klotho levels×TyG 5402 98,360.24 ± 57,765.66 102,384.89 ± 68,119.63 4.676 0.031*

Note: 1. Percentage = CVDs / Overall ∗ 100 %; 2. *P < 0.05; **P < 0.01.