TABLE 2.
Antimicrobial activity for the three most frequently isolated species of nonpigmented RGM
| Species | Antimicrobial agenta
|
|
|---|---|---|
| >90% susceptible or intermediate (% if <100%) | <90% susceptible or intermediate (approx. % susceptibility/intermediate) | |
| M. fortuitum group | Amikacin, cefoxitin,c ciprofloxacin, gatifloxacin, imipenem, levofloxacin, linezolid (96%),f sulfamethoxazole or trimethoprim-sulfamethoxazole | Clarithromycin (80%),b doxycycline (46%),d vancomycin (38%)e |
| M. abscessus | Amikacin (98%),d cefoxitin (95%),h clarithromycinb | Ciprofloxacin (<1%),g doxycycline (4%),d imipenem (57%),h linezolid (48%) |
| M. chelonae | Amikacin (97%), clarithromycin,b gatifloxacin (96%),i linezolid (94%),f tobramycin | Ciprofloxacin (19%),g doxycycline (26%),d imipenem (40%)h |
a
Data given in exact percentages are referenced in the publications in the footnotes; otherwise, approximate percent positive is given.
b
Reference 20.
c
Excludes M. fortuitum third biovar sorbitol positive (proposed M. houstonense), of which >90% are resistant (194).
d
Reference 171.
e
C. J. Crist, R. J. Wallace Jr., B. A. Brown-Elliott, and L. B. Mann, Abstr. 101st Gen. Meet. Am. Soc. Microbiol 2001, abstr. U-35, 2001.
f
Reference 195.
g
Reference 187.
h
Reference 192.
i
B. A. Brown-Elliott, R. J. Wallace Jr., and C. J. Crist, Program Abstr. 41st Intersci. Conf. Antimicrob. Agents Chemother., abstr. E-723, 2001.