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. 2025 Nov 26;17(11):10407–10416. doi: 10.21037/jtd-2025-1823

Table 1. Summary of patient characteristics.

Variable All M/T ratio ≥1 M/T ratio <1 P value
Age (years) 64 [56–70] 62.8±11.3 63.0±9.29 0.96
Sex 0.20
   Male 28 (45.9) 25 (41.0) 3 (4.9)
   Female 33 (54.1) 25 (41.0) 8 (13.1)
BMI (kg/m2) 22.4 [20.7–25.7] 22.5 [21.0–25.6] 20.9 [20.0–25.5] 0.45
Brinkman index 200 [0–690] 210 [0–667.5] 100 [50–630] 0.90
FEV1 (%) 95.8 [83.8–104.1] 95.0±13.6 95.2±20.8 0.96
FEV1/FVC (%) 77.5 [74.1–80.8] 77.3±5.62 78.1±9.00 0.68
DLCO (%) 65.5 [57.5–76.5] 68.6±13.3 63.6±20.8 0.32
Tumor location 0.19
   Upper/middle lobe 24 (39.3)/5 (8.1) 23 (37.7)/3 (4.9) 1 (1.6)/2 (3.2)
   Lower lobe 32 (52.5) 24 (39.3) 8 (13.1)
Tumor diameter on CT (mm) 6.2 [5.0–7.3] 6.0 [4.8–7.3] 7.6 [7.1–8.8] 0.01
Tumor depth (mm) 21.1 [14.2–27.9] 20.4±9.83 27.8±7.56 0.02
Marking position 0.10
   Prone 32 (52.5) 29 (47.5) 3 (4.9)
   Supine 29 (47.5) 21 (34.4) 8 (13.1)
Lipiodol spot (mm) 11.4 [10.3–12.7] 11.42±2.04 11.81±1.53 0.56
Lipiodol localization 0.74
   Shallow 24 (39.3) 19 (31.1) 5 (8.2)
   Deep 37 (60.7) 31 (50.8) 6 (9.8)
3D-deviation† (mm) 10.5 [7.4–14.0] 10.25 [7.10–15.30] 12.40 [9.25–13.15] 0.57
Surgical procedure 0.66
   VATS 55 (90.2) 47 (77.0) 8 (13.1)
   Open 6 (9.8) 3 (4.9) 3 (4.9)
Lipiodol marking-related complications 11 (18.0) 9 (14.7) 2 (3.2) >0.99
Postoperative complications (C-D) >0.99
   II–III 5 (8.2) 4 (6.5) 1 (1.6)
   IV–V 0 0 0
Tumor diameter (mm) 7 [5–8] 6 [5–8] 8 [7–9] 0.046
Surgical margin (mm) 13 [8–16] 15 [10–18] 7 [5–7] <0.01

Values are expressed as mean [range], mean ± SD, or n (%), as appropriate according to the distribution of data. †, 3D-deviation: distance between lipiodol spot and lesion. 3D, three-dimensional; BMI, body mass index; C-D, Clavien-Dindo classification; DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; M/T, margin-to-tumor; SD, standard deviation; VATS, video-assisted thoracic surgery.