NF1	Neurofibromatosis Type 1
cNFs	cutaneous neurofibromas
pNFs	plexiform neurofibromas
MPNSTs	malignant peripheral nerve sheath tumors
HGMD®	Human Gene Mutation Database
GAP	GTPase-activating protein
NLS	nuclear localization signal
CSRD	cysteine/serine-rich domain
TBD	tubulin-binding region
GRD	GAP-related domain
LRD	leucine-rich domain
PH	pleckstrin homology
CTD	C-terminal domain
SBR	syndecan-binding region
SynGAP	synaptic RasGAP
PAM	PI3K/AKT/mTOR
AC	adenylyl cyclase
GPCR	G protein-coupled receptors
5-HT6r	5-hydroxytryptamine receptor 6
LRPPRC	leucine-rich pentatricopeptide-repeat-containing protein
APP	amyloid precursor protein
CALMs	café-au-lait macules
LOH	loss of heterozygosity
PRC2	Polycomb Repressive Complex 2
AAV	adeno-associated virus
HSV	herpes simplex virus
CAR-T	chimeric antigen receptor T cell
oHSV	oncolytic herpes simplex virus
T-VEC	Talimogene laherparepvec
DLT	dose-limiting toxicities
MTD	maximum tolerated dose
CART	Antigen-specific cytokine-activated T cells
CTLs	cytotoxic T lymphocytes
DCvac	dendritic cell vaccine
LGG	low-grade glioma
rAAVs	recombinant adeno-associated viruses
hSCs	human Schwann cells
C10	C-terminal 10 AA of HRAS domain
C24	C-terminal 24 AA of KRAS4B
IF	Immunofluorescence
hNu	human nuclear antigen
RTKs	receptor tyrosine kinases
HDACis	histone deacetylase inhibitors