A. muciniphila	Akkermansia muciniphila
ADT	Androgen deprivation therapy
AR	Androgen receptor
AHR	Aryl hydrocarbon receptor
CRPC	Castration-resistant prostate cancer
Dehydroepiandrosterone	DHEA
FMT	Fecal microbiota transplantation
GI	Gastrointestinal
GZMB	Granzyme B
GM	Gut microbiome
HFD	High-fat diet
HSPC	Hormone-sensitive prostate cancer
ICI	Immune checkpoint inhibitors
IGF-1	Insulin-like growth factor 1
IL-2	Interleukin-2
IL-6	Interleukin-6
IL-12	Interleukin-12
LPS	Lipopolysaccharide
mTOR	Mechanistic target of rapamycin
NK	Natural killer
PAMPs	Pathogen-associated molecular patterns
PRRs	Pattern-recognition receptors
PD	Pharmacodynamics
PK	Pharmacokinetics
PTEN	Phosphatase and tensin homolog
PI3K	Phosphatidylinositol 3-kinase
PAHs	Polycyclic aromatic hydrocarbons
PIA	Proliferative inflammatory atrophy
PIN	Prostatic intraepithelial neoplasia
PSA	Prostate specific antigen
SCC	Prostatic small cell carcinoma
AKT	Protein kinase B
RT	Radiotherapy
SCFAs	Short-chain fatty acids
TPH1	Tryptophan hydroxylase 1
TNF	Tumor necrosis factor
TME	Tumor-promoting microenvironment