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. 2025 Nov 29;26(23):11608. doi: 10.3390/ijms262311608
AcAld acetaldehyde
ADH alcohol dehydrogenase
ALDH2 aldehyde dehydrogenase-2
ALD alcohol-associated liver disease
Alda-1 N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide
ALT alanine aminotransferase
CBE chronic binge ethanol treatment
CC3 cleaved caspase-3
Col-1 collagen-1
COX4 cytochrome c oxidase IV
CTR control
CYP2E1 cytochrome-P450 2E1
DMSO dimethyl sulfoxide
EtOH ethanol
FAO fatty acid oxidation
GCase β-glucocerebrosidase/D-glucosyl-N-acylsphingosine glucohydrolase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPR91 G-protein coupled receptor-91
HSC hepatic stellate cell
hTERT-HSC immortal human HSC
IL-1β interleukin-1β
JO2 oxygen consumption
LAMP2 lysosomal-associated membrane protein-2
MAA malondialdehyde-acetaldehyde adducts
MAP1LC3/LC3 microtubule-associated protein 1 light chain 3
MB mitochondrial biogenesis
mtDAMPs mitochondrial damage-associated molecular patterns
mtDepo mitochondrial depolarization
mtDNA mitochondrial DNA
MDVs mitochondria-derived vesicles
NAD+ nicotinamide adenine dinucleotide
ND3 NADH dehydrogenase-3
nDNA nuclear DNA
NLRP3 NOD-like receptor protein 3
OXPHOS oxidative phosphorylation
p62 ubiquitin-autophagy adaptor 62
PI3K Class III phosphoinositide 3-kinase
PGC1α peroxisome proliferator-activated receptor gamma coactivator-1 alpha
PINK1 PTEN-induced putative kinase 1
qPCR quantitative polymerase chain reaction
SIAM swift increase in alcohol metabolism
αSMA smooth muscle α-actin
TFAM mitochondrial transcription factor-A
TFEB transcription factor-EB
TLR9 toll-like receptor 9
TMRM tetramethylrhodamine methylester
TNFα tumor necrosis factor-α
ΔΨ membrane potential