| PD | Parkinson’s disease |
| cfDNA | Cell-free DNA |
| cf-ntDNA | Nuclear derived cell-free DNA |
| cf-mtDNA | Mitochondrially derived cell-free DNA |
| CSF | Cerebrospinal fluid |
| LBs | Lewy bodies |
| SN | Substantia nigra |
| LRRK2 | Leucine rich repeat kinase 2 |
| CAD | Caspase-activated DNase |
| dsDNA | Double-stranded DNA |
| NETs | Neutrophil extracellular traps |
| ROS | Reactive oxygen species |
| AD | Alzheimer’s disease |
| RNA | Ribonucleic acids |
| ASO | Antisense oligonucleotide |
| EVs | Extracellular vesicle |
| DAMPs | Damage-Associated Molecular Patterns |
| tRNA | Transfer RNA |
| rRNA | Ribosomal RNA |
| ER | Endoplasmic reticulum |
| FIS1 | Mitochondrial fission protein 1 |
| DRP1 | Dynamic-related protein 1 |
| MFN1/2 | Mitofusion proteins 1 and 2 |
| LIR | LC3 interacting region |
| PINK1 | PTEN-induced putative kinase 1 |
| PTEN | Phosphatase and tensin homologue deleted on chromosome 10 |
| TOM | Translocase of the outer membrane |
| TIM | Translocase of the inner membrane |
| PARL | Presenilin-associated rhomboid-like protein |
| OMM | Outer mitochondrial membrane |
| OPTN | Optineurin |
| NDP52 | Nuclear dot protein 52 |
| CALCOCO2 | Calcium-binding and coiled-coil domain-containing protein 2 |
| MDVs | Mitochondrially derived vesicles |
| cGAS | Cyclic GMP/AMP synthase |
| cGAMP | Cyclic guanosine monophosphate–adenosine monophosphate |
| STING | Stimulator of interferon genes |
| TCA | Tricarboxylic acid cycle |
| PRRs | Pattern recognition receptors |
| TLRs | Toll-like receptors |
| NOD | Nucleotide-binding oligomerization domain |
| NLRs | Nucleotide-binding oligomerization domain like receptors |
| HD | Huntington’s disease |
| ALS | Amyotrophic lateral sclerosis |
| MS | Multiple sclerosis |
| IRF3 | Interferon regulatory factor 3 |
| IKK | IkappaB kinase |
| TBK1 | TANK-binding kinase 1 |
| qPCR | Quantitatively polymerase chain reaction |
| PCR | Polymerase chain reaction |
| NGS | Next Generation Sequencing |
| TNF | Tumor necrosis factor |
| IFNɣ | Interferon gamma |
| IL-6 | Interleukin 6 |