Table 3.
Effects of pulse high-volume haemofiltration on haemodynamic variables
| Variables | Pre-PHVHF | Mid-PHVHF | End-PHVHF | 6 hours after PHVHF | 12 hours after PHVHF | P |
| Noradrenaline Dose (μg/min) | 48 (0–114) | 40 (0–97)* | 40 (0–93) | 40 (0–69)* | 33 (0–67)** | 0.001 |
| SBP (mmHg) | 124.32 ± 25.63 | 126.64 ± 22.10 | 133.00 ± 24.55 | 133.06 ± 23.88 | 133.16 ± 26.15 | 0.04 |
| MAP (mmHg) | 82.16 ± 18.31 | 85.02 ± 18.82 | 86.88 ± 17.56 | 87.76 ± 20.65 | 87.26 ± 22.05 | NS |
| CI (l/min per m2) | 3.4 ± 1.1 | 3.4 ± 1.2 | 3.5 ± 1.0 | 3.5 ± 1.1 | 3.5 ± 1.2 | NS |
| HR (beats/min) | 97.28 ± 25.53 | 99.62 ± 22.94 | 100.06 ± 21.79 | 99.94 ± 20.71 | 95.62 ± 20.66 | 0.04 |
| Temperature (°C) | 36.7 ± 1.0 | 36.8 ± 0.8 | 36.8 ± 0.8 | 36.9 ± 0.8 | 36.7 ± 0.9 | NS |
| PaO2/FiO2 | 230.9 ± 109.1 | 232.8 ± 104.4 | 243.0 ± 105.6 | 230.2 ± 109.9 | 234.6 ± 106.4 | NS |
Normally distributed values are reported as mean ± standard deviation, and the statistical test used was analysis of variance for repeated measurements. Non-normally distributed values are reported as median (25th to 75th percentile), and P value was determined using Friedman's two-way analysis of varience with post-hoc Wilcoxon signed rank test. *P < 0.05, **P < 0.01 versus baseline. HR, heart rate; CI, cardiac index; MAP, mean arterial pressure; PaO2/FiO2, arterial oxygen tension/fractional inspired oxygen; PHVHF, pulse high-volume haemofiltration; SBP, systolic blood pressure.