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. Author manuscript; available in PMC: 2026 Jul 2.
Published before final editing as: Reg Anesth Pain Med. 2025 Jul 2:rapm-2025-106783. doi: 10.1136/rapm-2025-106783

Table 1. Patient clinical and demographic characteristics stratified by app randomization.

Characteristic Education App (N = 303) Control App (N = 303) Absolute Standardized Difference Missing, n (%)

Age, years, median [Q1, Q3] 50 [37, 62] 49 [37, 60] 0.073 0 (0)
Body Mass Index, kg m-2, mean (SD) 36 (10) 34 (9) 0.123 0 (0)
Sex, n (%) 0.132 0 (0)
 Male 116 (38) 97 (32)
 Female 186 (61) 205 (68)
 Other 1 (0.3) 1 (0.3)
Race, n (%) 0.198 5 (0.8)
 White 262 (87) 259 (86)
 Black or African American 20 (7) 24 (8)
 American Indian 4 (1) 1 (0.3)
 Asian 2 (0.7) 3 (1.0)
 Multiracial 5 (2) 1 (0.3)
 Other 8 (3) 12 (4)
Ethnicity: Hispanic or Latino, n (%) 15 (5) 16 (5) 0.014 1 (0.2)
Activated Decision Support Tool, 155 (51) 151 (50) 0.026 0 (0)
Surgical Specialty, n (%) 0.235 0 (0)
General 153 (51) 137 (45)
Thoracic 17 (6) 24 (8)
Colorectal 4 (1) 3 (1)
Obstetric 14 (5) 24 (8)
Gynecologic 20 (7) 19 (6)
Neurological 16 (5) 21 (7)
Orthopedic 35 (12) 33 (11)
Urologic 25 (8) 25 (8)
Vascular 2 (0.7) 1 (0.3)
Ophthalmic, OMF, Plastic ENT or Plastic 11 (4) 13 (4.3)
Not specified 2 (0.7) 0 (0.0)
Multiple 4 (1.3) 3 (1.0)
PROMIS Sleep Disturbance score, mean (SD) 52 (5) 52 (5) 0.114 0 (0)
PHQ-8 score, mean (SD) 5 (4) 5 (4) 0.027 0 (0)
Insurance, n (%) 0.155 1 (0.2)
Medicare 41 (14) 41 (14)
Medicaid 26 (9) 36 (12)
Private 198 (66) 189 (62)
Self-pay 7 (2) 12 (4)
Multiple 30 (10) 25 (8)
Substance use disorder, n (%) 6 (2) 5 (2) 0.025 0 (0)
Opioid use, n (%) 20 (7) 20 (7) <0.001 0 (0)
Benzodiazepine use, n (%) 28 (9) 19 (6) 0.111 0 (0)
Antidepressant use, n (%) 85 (28) 72 (24) 0.098 0 (0)
Gabapentinoid use, n (%) 78 (26) 66 (22) 0.093 0 (0)
Multiple procedures during admission, n (%) 7 (2) 7 (2) <0.001 0 (0)
Length of stay, days, median [Q1, Q3] 2 [1, 4] 2 [1, 4] 0.020 0 (0)
Pain score at discharge, mean (SD) 3 (3) 4 (3) 0.017 4 (0.7)
Cumulative opioids in hospital, MME, median [Q1, Q3] 96 [58, 163] 100 [57, 175] 0.005 0

Absolute standardized difference was calculated by dividing the difference in means by SD. Absolute standardized difference greater than 0.159 (bolded) was considered to indicate imbalance. Pain score at discharge was calculated using the visual analog scale. Medication use was identified preoperatively.

Abbreviations: ENT, ear nose and throat; OMF, oral and maxillofacial surgery; PROMIS, Patient-Reported Outcomes Measurement Information System; PHQ-8, Patient Health Questionnaire-8; Q1, First quartile; Q3, Third quartile; SD, standard deviation.