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. 2025 Dec 11;27:e84918. doi: 10.2196/84918

Table 3. Bivariate comparisons of characteristics by willingness to adopt large language models among health care professionals. Associations were tested using t tests for continuous variables and Chi-square tests for categorical variables.

Variables Willing Unwilling or uncertain P valuea
Sex, n (%) .927
 Male 69/116 (59.5) 72/124 (58.1)
 Female 47/116 (40.5) 52/124 (41.9)
Profession, n (%) .712
 Physician 75/116 (64.7) 84/124 (67.7)
 Nurse 41/116 (35.3) 40/124 (32.3)
Department, n (%) .751
 Internal medicine 27/116 (23.3) 27/124 (21.8)
 Surgery 22/116 (19) 19/124 (15.3)
 ICUb 22/116 (19) 25/124 (20.2)
 Emergency 25/116 (21.6) 35/124 (28.2)
 Other 20/116 (17.2) 18/124 (14.5)
Hospital affiliation, n (%) .137
 Nonaffiliated 55/116 (47.4) 46/124 (37.1)
 Affiliated 61/116 (52.6) 78/124 (62.9)
Hospital type, n (%) .938
 Oncology 22/116 (19) 22/124 (17.7)
 General 94/116 (81) 102/124 (82.3)
Province’s economic level, n (%) <.001
 Low 11/116 (9.5) 35/124 (28.2)
 Medium 34/116 (29.3) 59/124 (47.6)
 High 71/116 (61.2) 30/124 (24.2)
Frequency of digital tool use, n (%) <.001
 Rarely 5/116 (4.3) 33/124 (26.6)
 Occasionally 36/116 (31) 49/124 (39.5)
 Often 75/116 (64.7) 42/124 (33.9)
Previous awareness of LLMsc, n (%) <.001
 Yes 93/116 (80.2) 73/124 (58.9)
 No 23/116 (19.8) 51/124 (41.1)
Previous use of LLMs, n (%) <.001
 Yes 56/116 (48.3) 32/124 (25.8)
 No 60/116 (51.7) 92/124 (74.2)
Received AId or informatics training, n (%) .030
 Yes 53/116 (45.7) 39/124 (31.5)
 No 63/116 (54.3) 85/124 (68.5)
Age (years), mean (SD) 39.5 (6.4) 40.3 (6.6) .382
Years of clinical experience, mean (SD) 10.7 (5.1) 9.2 (4.4) .017
Trust in LLMs (1-5), mean (SD) 3.20 (1.22) 2.78 (1.26) .011
Perceived usefulness (1-5), mean (SD) 3.70 (1.11) 2.52 (1.02) <.001
Privacy concerns (1-5), mean (SD) 2.82 (1.20) 3.62 (1.33) <.001
Clarity on legal responsibility (1-5), mean (SD) 3.41 (1.29) 2.84 (1.29) <.001
a

P<.05 was considered statistically significant.

b

ICU: intensive care unit.

c

LLM: large language model.

d

AI: artificial intelligence.