TABLE 1.
Drug, dose, and duckling no. | DHBV titer (pg/ml)a |
---|---|
ETV, 1 mg/kg | |
126 | 15,273 |
133 | 9,447 |
139 | 41,742 |
154 | 23,058 |
161 | 45,961 |
204b | 67,045 |
ETV, 0.1 mg/kg | |
127 | 11,767 |
129 | 15,811 |
145 | 26,953 |
221 | 44,897 |
229 | 41,284 |
273b | 64,914 |
ETV, 0.01 mg/kg | |
132 | 17,473 |
143 | 27,390 |
151 | 43,399 |
153 | 38,590 |
155 | 12,098 |
158 | 54,316 |
3TC, 25 mg/kg | |
148 | 30,406 |
157 | 35,567 |
247 | 49,264 |
281 | 13,079 |
283b | 42,812 |
299 | 21,966 |
None (control) | |
136 | 33,514 |
142 | 46,174 |
150 | 14,775 |
242b | 41,098 |
246 | 31,521 |
278 | 22,159 |
Baseline titers were performed on day −4.
Duckling that was congenitally infected with DHBV.