TABLE 3.
Susceptibilities to beta-lactams distributed by species and ESBL gene typea
| Species and ESBL type | No. of isolates | MIC50/MIC90 of beta-lactam (μg/ml)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Piperacillin | Cephalothin | Ceftriaxone | Cefotaxime | Ceftazidime | Cefepime | Cefoxitin | Aztreonam | Imipenem | ||
| P. mirabilis | ||||||||||
| TEM+ | 127 | >256/>256 | >256/>256 | 4/8 | 8/16 | 4/16 | 4/16 | 4/8 | 0.5/2 | 1/2 |
| P. stuartii | ||||||||||
| TEM+ | 22 | >256/>256 | >256/>256 | 4/32 | 8/16 | 32/>256 | 2/>32 | 2/128 | 4/16 | 1/2 |
| K. pneumoniae | ||||||||||
| TEM+ | 32 | >256/>256 | >256/>256 | 4/32 | 4/32 | >256/>256 | 2/8 | 2/16 | 32/>256 | 0.25/0.5 |
| SHV+ | 104 | >256/>256 | >256/>256 | 8/32 | 8/32 | >256/>256 | 2/16 | 2/16 | >256/>256 | 0.25/0.5 |
| TEM+ and SHV+ | 34 | >256/>256 | >256/>256 | 8/32 | 8/32 | >256/>256 | 2/16 | 2/16 | >256/>256 | 0.25/0.25 |
| Non-TEM/non-SHV | 18 | >256/>256 | >256/>256 | 8/>256 | 8/32 | >256/>256 | 2/8 | 4/16 | >256/>256 | 0.25/0.5 |
| E. coli | ||||||||||
| TEM+ | 11 | >256/>256 | >256/>256 | 4/32 | 8/16 | 16/128 | 4/16 | 2/4 | 4/8 | 0.25/0.25 |
| SHV+ | 28 | >256/>256 | >256/>256 | 4/32 | 4/32 | 32/>256 | 1/8 | 2/4 | 16/>256 | 0.25/0.25 |
| E. aerogenes | ||||||||||
| TEM+ | 11 | >256/>256 | >256/>256 | 8/16 | 8/16 | >256/>256 | 1/2 | >256/>256 | 16/32 | 0.25/0.25 |
| SHV+ | 14 | >256/>256 | >256/>256 | 16/64 | 16/32 | >256/>256 | 2/16 | >256/>256 | 64/>256 | 0.25/0.5 |
MICs were measured by the quantitative E-test assay. Values are not reported when fewer than 10 isolates were available.