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. 2025 Nov 28;6:1706912. doi: 10.3389/fresc.2025.1706912

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© 2025 Ladell, Golden, Oliemans, Walls, Manocha and Fletcher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bar graph showing the Visual Analog Scale (VAS) in millimeters for hEDS and control groups at 80%, 100%, and 120% preferred walking speed. hEDS group (grey bars) shows higher VAS scores with significant differences indicated by asterisks compared to the control group (black bars). — Pain following walking at 80%, 100% and 120% preferred walking speed. Mean ± SD HSD/hEDS and CON are shown as grey and black bars, respectively. Individual participant ratings are shown as open or filled circles for hEDS and CON, respectively. *indicate significant group differences (p < 0.05), **indicate significant group differences (p < 0.01), *** indicate significant group differences (p < 0.001).