TABLE 3.

Antifungal activities of conventional and new antifungal drugs against 13 clinical S. apiospermum isolates

Incubation period and antifungal	MIC (μg/ml)
	Range	Geometric mean	50%	90%
48 h
Miconazole	0.125	0.34	0.25	1
Terbinafine	2–>32	32	32	>32
Itraconazole	0.03–2	0.35	0.5	2
UR-9825	0.03–1	0.13	0.125	1
Voriconazole	0.03–0.5	0.09	0.125	0.25
Amphotericin B	0.5–8	1.72	2	4
Posaconazole	0.125–1	0.42	0.5	1
Nystatin	2–16	5.99	4	16
Liposomal nystatin	2–16	5.99	4	16
72 h
Miconazole	0.25–1	0.58	0.5	1
Terbinafine	32–>32	>32	>32	>32
Itraconazole	0.25–8	0.78	0.5	4
UR-9825	0.06–2	0.41	0.5	2
Voriconazole	0.03–0.5	0.17	0.25	0.5
Amphotericin B	1–16	2.97	4	16
Posaconazole	0.25–2	0.79	1	2
Nystatin	4–32	12.70	16	32
Liposomal nystatin	4–16	11.99	16	16