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. 2002 Jan;46(1):62–68. doi: 10.1128/AAC.46.1.62-68.2002

TABLE 5.

Cutoffs in distributions of MICs determined from the normal plots

Antifungal MIC cutoff (μg/ml)a
S. prolificans
S. apiospermum
48 h 72 h 48 h 72 h
Miconazole 4 (0.83) 16 (0.77) 0.25 (0.87b) 0.25 (0.83)
Terbinafine 4 (0.86) 16 (0.88) 16 (0.60) NDc
Itraconazole 32 (0.29) ND 0.25 (0.94b) 1 (0.89b)
UR-9825 2 (0.79) 4 (0.81) 0.06 (0.85) 0.25 (0.95b)
Voriconazole 1 (0.80) 2 (0.78) 0.06 (0.88b) 0.125 (0.94b)
Amphotericin 8 (0.84) 8 (0.60) 1 (0.89b 2 (0.84)
Posaconazole ND ND 0.25 (0.88b) 0.25 (0.90b)
Nystatin 8 (0.72) 16 (0.61) 4 (0.86b) 8 (0.85)
Liposomal nystatin 8 (0.69) ND 4 (0.80) 8 (0.58)
a

The cutoffs were determined graphically from the normal plots (the values in parentheses are the W correlation coefficients between the distribution of the MICs and the normal distribution obtained by the Shapiro-Wilk test; P < 0.05).

b

P > 0.05.

a

ND, not determined.