TABLE 2.

Relative host tolerance of polyamine analogs

Dose (mg/kg)	No. of deaths/group	Day of death	Avg weight loss or gain (g) 1 day posttreatment
SL-11061
0	0		+1.7
1	0		+0.8
2.5	0		0
5	0		−0.1
10	0		+0.7
SL-11091
0	0		+1.4
5	0		+2.6
10	0		+2.4
15	0		+1.0
20	0		+1.9
25	0		+1.1
SL-11093
0	0		+4.1
5	0		+2.2
10	0		+2.4
15	0		+2.8
20	0		+1.6
25	0		+2.2
50	0		−0.1
100	2	5, 8	−6.5
150	3	4, 8, 8
SL-11099
0	0		+0.45
1	0		−1.17
2.5	0		+1.16
5	0		0
10	0		−0.58
15	0		+0.16
25	0		−1.34
50	0		−2.34
SL-11144
0	0		+1.7
0	0		+4.1
1	0		+1.5
2.5	0		−0.9
5	0		+0.2
10	0		+0.3
15	3	9, 9, 15
25	3	3, 3, 3
SL-11158
0	0		+1.7
1	0		+1.5
2.5	0		+1.0
5	0		+0.7
10	0		+0.1
15	1	8	−1.5
25	3	3, 3, 3