TABLE 4.
Effects of CAS and AMB on creatinine, urea nitrogen, ALT, AST, and bilirubin levels in the serum of persistently neutropenic rabbits with pulmonary aspergillosis
| Treatment group (n) | Level (mean ± SEM) in serum of:
|
||||
|---|---|---|---|---|---|
| Creatinine (mg/dl) | Urea nitrogen (mg/dl) | ALT (U/liter) | AST (U/liter) | Bilirubin (mg/dl) | |
| Control (12) | 0.95 ± 0.06 | 20.25 ± 1.41 | 89.08 ± 26.85 | 100.00 ± 60.45 | 0.27 ± 0.06 |
| CAS (35) | 0.98 ± 0.05 | 18.31 ± 1.27 | 66.43 ± 14.08 | 35.86 ± 9.40 | 0.32 ± 0.05 |
| AMB (6) | 2.00 ± 0.19a | 89.50 ± 12.60a | 58.67 ± 27.55 | 31.83 ± 25.44 | 0.12 ± 0.01 |
a
P < 0.001; calculated by using ANOVA with Bonferroni’s correction for multiple comparisons.