TABLE 2.
Comparison of clearance of fungemia in patients with AIDS and histoplasmosis treated with itraconazole versus fluconazolea
| Wk of study | No. of patients with negative blood cultures/no. with cultures drawn after treatment with:
|
Pb | |
|---|---|---|---|
| Itraconazole | Fluconazole | ||
| 0 | 0/31 | 0/52 | Not appropriate |
| 4 | 24/26 (92.3%) | 26/42 (61.9%) | 0.017 |
| 8 | 23/23 (100%) | 33/35 (94.3%) | 0.730 |
| 12 | 23/23 (100%) | 24/27 (88.9%) | 0.298 |
a
This analysis was restricted to patients with positive fungal blood cultures at enrollment or at week 1 if the baseline culture was negative or not done.
b
Adjusted for multiple comparisons using Bonferroni’s procedure.