Table 3.
Comparison of the Results of Different Studies on the Relationship Between Molecular Subtypes and Histological Types of Endometrial Cancer
| Studies | Endometrioid Carcinoma | Serous Carcinoma | Clear Cell Carcinoma | Squamous Cell Carcinoma | Mixed Carcinoma | Others | References |
|---|---|---|---|---|---|---|---|
| Present study | Higher POLE mutant proportion vs other types | Proportion of p53 abnormal most | Proportion of p53 abnormal is second most | ||||
| Americans | Higher POLE mutant proportion vs other types | Proportion of p53 abnormal most | Proportion of p53 abnormal is second most | PMID: 37245486 | |||
| A population from Zhejiang, China | Proportion of p53 abnormal most | Proportion of p53 abnormal most | PMID: 40302811 | ||||
| A population from Finland | Proportion of p53 abnormal most | PMID: 38303106 | |||||
| A population from Japan | Proportion of p53 abnormal most | PMID: 35002543 | |||||
| A study based on the data from Cancer Genome Atlas (TCGA) | Proportion of p53 abnormal is higher vs endometrioid carcinoma | PMID: 26556035 |
Abbreviation: POLE, DNA polymerase epsilon.