FIG. 2.
Effects of TAK-457 and reference antifungal agents against pulmonary infection caused by A. fumigatus 437 in neutropenic CDF1 mice. Antifungal agents were administered intravenously once a day for 5 days starting 2 h after infection (n = 10). Agents: vehicle (•), TAK-457 at 10 mg/kg (○) and 3 mg/kg (◊), amphotericin B at 1 mg/kg (□), fluconazole at a dose of 10 mg/kg (▵).
