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. 2025 Oct 18;312(6):2001–2010. doi: 10.1007/s00404-025-08163-8

Table 2.

Specificity and sensitivity of the measured hematologic and inflammatory indices in the determination of hyperemesis gravidarum

AUC p value 95% CI Sensitivity Specificity PPV NPV
Lower bound Upper bound
NLR > 5.67 0.608 0.002 0.545 0.668 25.8 94 87.2 44.3
PLR > 154.5 0.610 0.002 0.547 0.669 44.0 81 78.7 47.6
SII > 948.41 0.636  < 0.001 0.575 0.695 55.3 70 74.6 49.6
PIV > 866.51 0.637  < 0.001 0.575 0.696 35.2 88 82.4 46.1

AUC area under the curve, CI confidence interval, PPV positive predictive value, NPV negative predictive value, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, SII systemic immune-inflammation index, PIV pan-immune-inflammation score

*p values in bold are statistically significant