TABLE 2.

Antimicrobial susceptibilities and MIC distributions for 4,725 S. pneumoniae isolates by penicillin susceptibility status^a

Antimicrobial and phenotype	No. of isolates for which the MIC (μg/ml) was as follows:
	≤0.004	0.008	≤0.015	0.03	0.06	≤0.12	0.25	0.5	1	2	4	8	16	32	>32
Faropenemb
All	1,655	1,247	172	173	168	358	592	209	148	3
Penicillin susceptible	1,646	1,234	138	42	12	6
Penicillin intermediate	8	13	34	131	155	333	408	63	9
Penicillin resistant	1	0	0	0	1	19	184	146	139	3
Amoxicillin-clavulanate
All			2,503	445	171	125	148	305	572	224d	184e	46ff	2
Penicillin susceptible			2,490	427	113	36	7	4	1
Penicillin intermediate			13	18	58	89	141	299	423	93	20
Penicillin resistant								2	148	131	164	46	2
Cefuroxime
All				3,017	217	116	122d	226e	716f	217	68	25	1
Penicillin susceptible				2,942	100	29	7
Penicillin intermediate						75	117	87	115	220	486	50	3	1
Penicillin resistant										6	230	167	65	24	1
Imipenem
All			3,129	204	201	495d	454e	231e	11f
Penicillin susceptible			3,026	44	6	0	2
Penicillin intermediate			103	160	194	450	219	28
Penicillin resistant					1	45	233	20	11
Ceftriaxone
All			2,688	323	200	221	344	518d	295e	76f	53	7
Penicillin susceptible			2,662	264	96	49	6	1
Penicillin intermediate			26	59	104	172	332	377	72	8	4
Penicillin resistant							6	140	223	68	49	7

^aOf the 4,725 isolates of S. pneumoniae, 3,078 were penicillin susceptible, 1,154 were penicillin intermediate, and 493 were penicillin resistant.

^bNCCLS breakpoints are not available for faropenem.

^cBoldface numbers represent the points at which the MIC₉₀ was achieved.

^dNCCLS MIC interpretive breakpoint for susceptibility.

^eNCCLS MIC interpretive breakpoint for intermediate.

^fNCCLS MIC interpretive breakpoint for resistance.