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Comparison of the efficacy of abacavir on cell infection of CEM cells with HIV strains IIIB and MN versus cocultivation of CEM cells with HIV-infected H9 cells at a 100:1 ratio. The dose of drug was 0.42 μg/ml, which was the calculated value for a constant exposure of cells to the simulated 500-mg dose. HIV p24 was measured in cell supernatants of the cultures at day 7 postinfection.
