TABLE 3.
Cytotoxicities of T-705 and reference compounds
Cell line | CC50 (μg/ml)a
|
|||
---|---|---|---|---|
T-705 | GS 4071 | Amantadine | Ribavirin | |
MDCK | >1,000 | >1,000 | 160 | 23 |
Vero | >1,000 | >1,000 | 140 | 59 |
HEL | >1,000 | >1,000 | 18 | 19 |
A549 | >1,000 | >1,000 | 81 | 75 |
HeLa | >1,000 | >1,000 | 89 | 11 |
HEp-2 | >1,000 | >1,000 | 91 | 7.8 |
The values are averages of results from two independent experiments.