TABLE 1.

Antimalarial activities and cytotoxicities of compounds isolated from S. spectabilis BCC 4785

Compound	Activity (IC50, μg/ml) against P. falciparum K1	Cytotoxicity (IC50, μg/ml) for:
		KB cells	BC-1 cells	Vero cells
Metacycloprodigiosin hydrochloridea	0.0050 ± 0.0010	0.36 ± 0.02	0.27 ± 0.01	1.35 ± 0.28
Bafilomycin A1a	0.041 ± 0.010	0.27 ± 0.03	0.20 ± 0.04	1.14 ± 0.04
Spectinabilin	7.8	0.10	0.80	20
Chloroquine diphosphateb	0.16	16	>20	>20
Artemisininb	0.0011	>20	>20	>20

^aAssays were performed in triplicate for these highly active compounds; values are means and standard deviations.

^bStandard antimalarial compounds.