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. 2025 Oct 21;47:e-rbgo85. doi: 10.61622/rbgo/2025rbgo85

Table 4. Comparison of response variables studied between participants treated with estriol or MFR.

Groups
Variables Estriol MFR Odds ratioa p-value
(n=15) (n=15)
Basal/parabasal cells before
<10 6(40.0) 5(33.3) 1.33 [0.30; 5.92] 0.7052
>10 9(60.0) 10(66.7)
Basal/parabasal cells after
<10 7(46.7) 7(46.7) 1.00 [0.24; 4.29] 1.0002
>10 8(53.3) 8(53.3)
Type of microbiota before - 0.2841
I - Presence of only Lactobacillus 4(26.7) 6(40.0)
Ila - Presence of other 4(26.7) 6(40.0)
bacteria, but predominance of Lactobacillus
Ilb - Observation of 4(26.7) 3(20.0)
Lactobacillus, but predominance of other bacteria
Ill - Absence of Lactobacillus, 3(20.0) 0(0.0)
presence of only other bacteria
Type of microbiota after
I - Presence of only 4(26.7) * 10(66.7) **
Lactobacillus
Ila - Presence of other 7(46.6) ** 1(6.7) *
bacteria, but predominance of Lactobacillus
IIb - Observation of 3(20.0) 3(20.0) - 0.0571
Lactobacillus, but predominance of other bacteria
III - Absence of Lactobacillus, 1(6.7) 1(6.7)
presence of only other bacteria
Lactobacillus before
Absent or rare 6(40.0) 4(26.7) 1.83 [0.39; 8.57] 0.4392
Moderate or numerous 9(60.0) 11(73.3)
Lactobacillus after
Absent or rare 5(33.3) 4(26.7) 1.37 [0.28; 6.61] 1.0001
Moderate or numerous 10(66.7) 11(73.3)
Coccobacilli or bacilli before
Absent or rare 12(80.0) 14(93.3) 0.28 [0.03; 3.12] 0.5981
Moderate or numerous 3(20.0) 1(6.7)
Coccobacilli or bacilli after
Absent or rare 12(80.0) 13(86.7) 0.61 [0.09; 4.34] 1.0001
Moderate or numerous 3(20.0) 2(13.3)
Coco grouped or in a chain before
Absent or rare 9(60.0) 11(73.3) 0.54 [0.12; 2.55] 0.4392
Moderate or numerous 6(40.0) 4(26.7)
Coco grouped or in a chain after
Absent or rare 12(80.0) 12(80.0) 1.00 [0.17; 5.99] 1.0001
Moderate or numerous 3(20.0) 3(20.0)
Candida before
Absent 15(100.0) 13(86.7) 5.74 0.4831
Present 0(0.0) 2(13.3) [0.25;130.50]
Candida after
Absent 10(66.7) 14(93.3) 0.14 [0.01; 1.41] 0.1691
Present 5(33.3) 1(6.7)
pH before
>6.1 6(40.0) 7(46.6)
5.6-6.0 0(0.0) 3(20.0)
5.1-5.5 5(33.3) 1(6.7) - 0.1211
4.7-5.0 4(26.7) 4(26.7)
pH after
>6.1 0(0.0) 4(26.7) - 0.1691
5.1-5.5 4(26.7) 3(20.0)
4.7-5.0 11(73.3) 8(53.3)
Change basal/parabasal cells
No change 14(93.3) 13(86.7) 2.15 [0.17; 26.69] 1.0001
Improvement 1(6.7) 2(13.3)
Microbiota change
Worse 4(26.7) 4(26.7) - 0.8951
No change 4(26.7) 6(40.0)
Improvement 7(46.6) 5(33.3)
Lactobacillus Change
Worse 2(13.3) 3(20.0) - 1.0001
No change 10(66.7) 9(60.0)
Improvement 3(20.0) 3(20.0)
Change Coccobacillus or bacilli
Worse 2(13.4) 1(6.7) - 0.3971
No change 11(73.3) 14(93.3)
Improvement 2(13.3) 0(0.0)
Change Coconuts grouped or in chains
- 1.0001
Worse 2(13.4) 3(20.0)
No change 8(53.3) 8(53.3)
Improvement 5(33.3) 4(26.7)
Candida Change
Worse 5(33.3) ** 0(0.0) * - 0.0421
No change 10(66.7) 14(93.3)
Improvement 0(0.0) 1(6.7)
pH change 0.6132
Worse 0(0.0) 2(13.3) -
No change 6(40.0) 6(40.0)
Improvement 9(60.0) 7(46.7)