7.

Spectra (NUS/MIST; 32/128; ¹H­{¹⁵N}-HSQC; ubiquitin) resulting from the Poisson Gap (PG) and Quantile (QS) algorithms in (a) and (b), respectively, are contrasted with (c) a spectrum employing a random unweighted (RU) schedule (including backfill of 6 samples) that resulted in severe artifactual noise. The dashed vertical lines indicate the positions of the displayed F1 slices, and the schedules are illustrated as well. A large gap occurred early, as well as another nearer the middle, both critical regions, where flaws of this magnitude illustrate the dangers of using RU schedules in sparse conditions, but also show that such large flaws are outside the scope of the TMPF corrective procedure.